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KMID : 0377519840090010079
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Chung-Ang Journal of Medicine
1984 Volume.9 No. 1 p.79 ~ p.87
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Experimental Brain Edema Induced by CO_2 Laser Irradiation
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Byun Bark-Jang
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Abstract
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The author studied the chronological changes in rat brain edema, induced by CO_2 laser irradiation (LI-group), by measuring brain water content. Water content was measured by gas-liquid chromatography (GLC). The changes of water content of laser induced brain edema was compared to that of brain edema produced by bipolar coagulation (BC-group). In both groups, water content increased significantly during the first three days after injury. It returned to nearly normal level on the fifth day, and remained unchanged thereafter. These findings suggested that the laser induced brain damage has a pattern similar ti that of traumatic origin. The clinical and histological findings were correlated well to the changes of water content. The water content of the corresponding area on the opposite side increased in most animals of high intensity LI-group but the increase was minimal. The GLC method was very convenient for determination of the extent of brain edema. Betamethasone was not so effective for brain edema induced by laser irradiation.
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